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HRG-β1-driven ErbB3 signaling induces epithelial–mesenchymal transition in breast cancer cells

BACKGROUND: Heregulin (HRG; also known as neuregulin) is a ligand for ErbB3. One of its isotypes, HRG-β1, binds to ErbB3 and forms heterodimers with other ErbB family members, thereby enhancing the proliferation and tumorigenesis of breast cancer cells. HRG stimulation may contribute to the progress...

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Detalles Bibliográficos
Autores principales:	Kim, Jinkyoung, Jeong, Hoiseon, Lee, Youngseok, Kim, Chungyeul, Kim, Hankyeom, Kim, Aeree
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750857/ https://www.ncbi.nlm.nih.gov/pubmed/23937725 http://dx.doi.org/10.1186/1471-2407-13-383

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