Rosai-Dorfman disease presenting with extensive cutaneous manifestation - Case report

Rosai-Dorfman disease is a benign, self-limited, idiopathic proliferative histiocytic disorder. It was first described in 1969 by Rosai and Dorfman. In its typical form the disease is characterized by extensive cervical lymphadenopathy associated with fever, polyclonal gammopathy and leukocytosis wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Leal, Paula Azevedo Borges, Adriano, Adrilena Lopes, Breckenfeld, Marcelle Parente, Costa, Igor Santos, de Sousa, Antônio Renê Diógenes, Gonçalves, Heitor de Sá
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750892/
https://www.ncbi.nlm.nih.gov/pubmed/23739703
http://dx.doi.org/10.1590/S0365-05962013000200014
Descripción
Sumario:Rosai-Dorfman disease is a benign, self-limited, idiopathic proliferative histiocytic disorder. It was first described in 1969 by Rosai and Dorfman. In its typical form the disease is characterized by extensive cervical lymphadenopathy associated with fever, polyclonal gammopathy and leukocytosis with neutrophilia. The skin is the most common site affected. Extranodal manifestations have been reported in 43% of cases. In this study, we report an atypical case of Rosai-Dorfman disease in a female with massive cutaneous manifestation on the thigh, associated with a minimal lymphadenopathy limited to the regional inguinal lymph nodes.

Ejemplares similares