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Non Hodgkin T cell lymphoma: an atypical clinical presentation
Cytotoxic lymphomas comprise a spectrum of peripheral T-cell lymphomas that can have a initial or late cutaneous presentation. We describe a 46-year-old man from Cape Verde, with a dermatosis involving his face and trunk, consisting of monomorphic papules with a smooth surface and both motor and sen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750894/ https://www.ncbi.nlm.nih.gov/pubmed/23739711 http://dx.doi.org/10.1590/S0365-05962013000200016 |
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author | Maio, Paula Bento, Diogo Vieira, Raquel Afonso, Ana Sachse, Fernanda Kutzner, Heinz |
author_facet | Maio, Paula Bento, Diogo Vieira, Raquel Afonso, Ana Sachse, Fernanda Kutzner, Heinz |
author_sort | Maio, Paula |
collection | PubMed |
description | Cytotoxic lymphomas comprise a spectrum of peripheral T-cell lymphomas that can have a initial or late cutaneous presentation. We describe a 46-year-old man from Cape Verde, with a dermatosis involving his face and trunk, consisting of monomorphic papules with a smooth surface and both motor and sensory polyneuropathy.The hypothesis of leprosy was supported by the clinical and initial hystopathological findings and the patient was referred to our hospital with suspected Hansen's disease. In the new skin and lymph node biopsies a lymphocyte population was identified whose immunohystochemistry study allowed the diagnosis of T-cell lymphoma with expression of cytotoxic markers. The patient was started on chemotherapy with initial remission of the skin lesions but, subsequently, progression of systemic disease. |
format | Online Article Text |
id | pubmed-3750894 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-37508942013-09-18 Non Hodgkin T cell lymphoma: an atypical clinical presentation Maio, Paula Bento, Diogo Vieira, Raquel Afonso, Ana Sachse, Fernanda Kutzner, Heinz An Bras Dermatol Case Report Cytotoxic lymphomas comprise a spectrum of peripheral T-cell lymphomas that can have a initial or late cutaneous presentation. We describe a 46-year-old man from Cape Verde, with a dermatosis involving his face and trunk, consisting of monomorphic papules with a smooth surface and both motor and sensory polyneuropathy.The hypothesis of leprosy was supported by the clinical and initial hystopathological findings and the patient was referred to our hospital with suspected Hansen's disease. In the new skin and lymph node biopsies a lymphocyte population was identified whose immunohystochemistry study allowed the diagnosis of T-cell lymphoma with expression of cytotoxic markers. The patient was started on chemotherapy with initial remission of the skin lesions but, subsequently, progression of systemic disease. Sociedade Brasileira de Dermatologia 2013 /pmc/articles/PMC3750894/ /pubmed/23739711 http://dx.doi.org/10.1590/S0365-05962013000200016 Text en ©2013 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Maio, Paula Bento, Diogo Vieira, Raquel Afonso, Ana Sachse, Fernanda Kutzner, Heinz Non Hodgkin T cell lymphoma: an atypical clinical presentation |
title | Non Hodgkin T cell lymphoma: an atypical clinical
presentation |
title_full | Non Hodgkin T cell lymphoma: an atypical clinical
presentation |
title_fullStr | Non Hodgkin T cell lymphoma: an atypical clinical
presentation |
title_full_unstemmed | Non Hodgkin T cell lymphoma: an atypical clinical
presentation |
title_short | Non Hodgkin T cell lymphoma: an atypical clinical
presentation |
title_sort | non hodgkin t cell lymphoma: an atypical clinical
presentation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750894/ https://www.ncbi.nlm.nih.gov/pubmed/23739711 http://dx.doi.org/10.1590/S0365-05962013000200016 |
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