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Passively transferred human NMO-IgG exacerbates demyelination in mouse experimental autoimmune encephalomyelitis

BACKGROUND: Neuromyelitis optica (NMO) is a devastating inflammatory disorder of the optic nerves and spinal cord characterized by frequently recurring exacerbations of humoral inflammation. NMO is associated with the highly specific NMO-IgG biomarker, an antibody that binds the aquaporin-4 water ch...

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Detalles Bibliográficos
Autores principales:	Saini, Harleen, Rifkin, Robert, Gorelik, Michael, Huang, Hwa, Ferguson, Zachary, Jones, Melina V, Levy, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750922/ https://www.ncbi.nlm.nih.gov/pubmed/23927715 http://dx.doi.org/10.1186/1471-2377-13-104

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