Highly aggressive pathology of non-functional parathyroid carcinoma

Parathyroid carcinoma is a rare malignant endocrine tumor accounting for only 0.5% to 5% of all primary hyperparathyroidism. Among these malignancies, only 10-25% are nonfunctioning. After the review of the literature we could only ascertain a number of 25 cases reported worldwide, since 1929, our c...

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Autores principales: Piciu, Doina, Irimie, Alexandru, Kontogeorgos, George, Piciu, Andra, Buiga, Rares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751033/
https://www.ncbi.nlm.nih.gov/pubmed/23915575
http://dx.doi.org/10.1186/1750-1172-8-115
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author Piciu, Doina
Irimie, Alexandru
Kontogeorgos, George
Piciu, Andra
Buiga, Rares
author_facet Piciu, Doina
Irimie, Alexandru
Kontogeorgos, George
Piciu, Andra
Buiga, Rares
author_sort Piciu, Doina
collection PubMed
description Parathyroid carcinoma is a rare malignant endocrine tumor accounting for only 0.5% to 5% of all primary hyperparathyroidism. Among these malignancies, only 10-25% are nonfunctioning. After the review of the literature we could only ascertain a number of 25 cases reported worldwide, since 1929, our case being the 26th, but the first with a very aggressive pathology, treated with chemotherapy scheme usually used for neuroendocrine tumors. Considering these facts, every single case presented is a step forward in defying the clinical presentation, for the awareness of the clinicians, and also in establishing standard adjuvant therapies.
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spelling pubmed-37510332013-08-24 Highly aggressive pathology of non-functional parathyroid carcinoma Piciu, Doina Irimie, Alexandru Kontogeorgos, George Piciu, Andra Buiga, Rares Orphanet J Rare Dis Letter to the Editor Parathyroid carcinoma is a rare malignant endocrine tumor accounting for only 0.5% to 5% of all primary hyperparathyroidism. Among these malignancies, only 10-25% are nonfunctioning. After the review of the literature we could only ascertain a number of 25 cases reported worldwide, since 1929, our case being the 26th, but the first with a very aggressive pathology, treated with chemotherapy scheme usually used for neuroendocrine tumors. Considering these facts, every single case presented is a step forward in defying the clinical presentation, for the awareness of the clinicians, and also in establishing standard adjuvant therapies. BioMed Central 2013-08-03 /pmc/articles/PMC3751033/ /pubmed/23915575 http://dx.doi.org/10.1186/1750-1172-8-115 Text en Copyright © 2013 Piciu et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor
Piciu, Doina
Irimie, Alexandru
Kontogeorgos, George
Piciu, Andra
Buiga, Rares
Highly aggressive pathology of non-functional parathyroid carcinoma
title Highly aggressive pathology of non-functional parathyroid carcinoma
title_full Highly aggressive pathology of non-functional parathyroid carcinoma
title_fullStr Highly aggressive pathology of non-functional parathyroid carcinoma
title_full_unstemmed Highly aggressive pathology of non-functional parathyroid carcinoma
title_short Highly aggressive pathology of non-functional parathyroid carcinoma
title_sort highly aggressive pathology of non-functional parathyroid carcinoma
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751033/
https://www.ncbi.nlm.nih.gov/pubmed/23915575
http://dx.doi.org/10.1186/1750-1172-8-115
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