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Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor
ABSTRACT: Intra-abdominal fibromatosis (IAF) commonly develops in patients who had abdominal surgery. In rare instances, it occurs subsequent to gastrointestinal stromal tumor (GIST). This special situation has clinical significance in imatinib era. About 1000 patients with GIST in our institution f...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751073/ https://www.ncbi.nlm.nih.gov/pubmed/23902675 http://dx.doi.org/10.1186/1746-1596-8-125 |
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author | Jiang, Dongxian He, Deming Hou, Yingyong Lu, Weiqi Shi, Yuan Hu, Qin Lu, Shaohua Xu, Chen Liu, Yalan Liu, Ju Tan, Yunshan Zhu, Xiongzeng |
author_facet | Jiang, Dongxian He, Deming Hou, Yingyong Lu, Weiqi Shi, Yuan Hu, Qin Lu, Shaohua Xu, Chen Liu, Yalan Liu, Ju Tan, Yunshan Zhu, Xiongzeng |
author_sort | Jiang, Dongxian |
collection | PubMed |
description | ABSTRACT: Intra-abdominal fibromatosis (IAF) commonly develops in patients who had abdominal surgery. In rare instances, it occurs subsequent to gastrointestinal stromal tumor (GIST). This special situation has clinical significance in imatinib era. About 1000 patients with GIST in our institution from 1993 to 2010 were re-evaluated based on their clinical and pathological data, the treatment strategies and the follow-up information. We identified 2 patients who developed IAF after GIST resection. Patient 1 was a 54 year-old male and had 5 cm × 4.5 cm × 3.5 cm jejunal GIST excised on February 22, 1994. Three years later, an abdominal mass with 7 cm × 6 cm × 3 cm was identified. He was diagnosed as recurrent GIST from clinical point of view. After excision, the second tumor was confirmed to be IAF. Patient 2 was a 45-year-old male and had 6 cm × 4 cm × 3 cm duodenal GIST excised on August 19, 2008. One year later, a 4 cm mass was found at the original surgical site. The patient refused to take imatinib until the tumor increased to 8 cm six months later. The tumor continued to increase after 6 months’ imatinib therapy, decision of surgical resection was made by multidisciplinary team. The second tumor was confirmed to be IAF with size of 17 cm × 13 cm × 11 cm. Although IAF subsequent to GIST is very rare, it is of clinical significance in imatinib era as an influencing factor for making clinical decision. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1076715989961803 |
format | Online Article Text |
id | pubmed-3751073 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-37510732013-08-24 Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor Jiang, Dongxian He, Deming Hou, Yingyong Lu, Weiqi Shi, Yuan Hu, Qin Lu, Shaohua Xu, Chen Liu, Yalan Liu, Ju Tan, Yunshan Zhu, Xiongzeng Diagn Pathol Case Report ABSTRACT: Intra-abdominal fibromatosis (IAF) commonly develops in patients who had abdominal surgery. In rare instances, it occurs subsequent to gastrointestinal stromal tumor (GIST). This special situation has clinical significance in imatinib era. About 1000 patients with GIST in our institution from 1993 to 2010 were re-evaluated based on their clinical and pathological data, the treatment strategies and the follow-up information. We identified 2 patients who developed IAF after GIST resection. Patient 1 was a 54 year-old male and had 5 cm × 4.5 cm × 3.5 cm jejunal GIST excised on February 22, 1994. Three years later, an abdominal mass with 7 cm × 6 cm × 3 cm was identified. He was diagnosed as recurrent GIST from clinical point of view. After excision, the second tumor was confirmed to be IAF. Patient 2 was a 45-year-old male and had 6 cm × 4 cm × 3 cm duodenal GIST excised on August 19, 2008. One year later, a 4 cm mass was found at the original surgical site. The patient refused to take imatinib until the tumor increased to 8 cm six months later. The tumor continued to increase after 6 months’ imatinib therapy, decision of surgical resection was made by multidisciplinary team. The second tumor was confirmed to be IAF with size of 17 cm × 13 cm × 11 cm. Although IAF subsequent to GIST is very rare, it is of clinical significance in imatinib era as an influencing factor for making clinical decision. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1076715989961803 BioMed Central 2013-07-31 /pmc/articles/PMC3751073/ /pubmed/23902675 http://dx.doi.org/10.1186/1746-1596-8-125 Text en Copyright © 2013 Jiang et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Jiang, Dongxian He, Deming Hou, Yingyong Lu, Weiqi Shi, Yuan Hu, Qin Lu, Shaohua Xu, Chen Liu, Yalan Liu, Ju Tan, Yunshan Zhu, Xiongzeng Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor |
title | Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor |
title_full | Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor |
title_fullStr | Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor |
title_full_unstemmed | Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor |
title_short | Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor |
title_sort | subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751073/ https://www.ncbi.nlm.nih.gov/pubmed/23902675 http://dx.doi.org/10.1186/1746-1596-8-125 |
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