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Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor

ABSTRACT: Intra-abdominal fibromatosis (IAF) commonly develops in patients who had abdominal surgery. In rare instances, it occurs subsequent to gastrointestinal stromal tumor (GIST). This special situation has clinical significance in imatinib era. About 1000 patients with GIST in our institution f...

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Autores principales: Jiang, Dongxian, He, Deming, Hou, Yingyong, Lu, Weiqi, Shi, Yuan, Hu, Qin, Lu, Shaohua, Xu, Chen, Liu, Yalan, Liu, Ju, Tan, Yunshan, Zhu, Xiongzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751073/
https://www.ncbi.nlm.nih.gov/pubmed/23902675
http://dx.doi.org/10.1186/1746-1596-8-125
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author Jiang, Dongxian
He, Deming
Hou, Yingyong
Lu, Weiqi
Shi, Yuan
Hu, Qin
Lu, Shaohua
Xu, Chen
Liu, Yalan
Liu, Ju
Tan, Yunshan
Zhu, Xiongzeng
author_facet Jiang, Dongxian
He, Deming
Hou, Yingyong
Lu, Weiqi
Shi, Yuan
Hu, Qin
Lu, Shaohua
Xu, Chen
Liu, Yalan
Liu, Ju
Tan, Yunshan
Zhu, Xiongzeng
author_sort Jiang, Dongxian
collection PubMed
description ABSTRACT: Intra-abdominal fibromatosis (IAF) commonly develops in patients who had abdominal surgery. In rare instances, it occurs subsequent to gastrointestinal stromal tumor (GIST). This special situation has clinical significance in imatinib era. About 1000 patients with GIST in our institution from 1993 to 2010 were re-evaluated based on their clinical and pathological data, the treatment strategies and the follow-up information. We identified 2 patients who developed IAF after GIST resection. Patient 1 was a 54 year-old male and had 5 cm × 4.5 cm × 3.5 cm jejunal GIST excised on February 22, 1994. Three years later, an abdominal mass with 7 cm × 6 cm × 3 cm was identified. He was diagnosed as recurrent GIST from clinical point of view. After excision, the second tumor was confirmed to be IAF. Patient 2 was a 45-year-old male and had 6 cm × 4 cm × 3 cm duodenal GIST excised on August 19, 2008. One year later, a 4 cm mass was found at the original surgical site. The patient refused to take imatinib until the tumor increased to 8 cm six months later. The tumor continued to increase after 6 months’ imatinib therapy, decision of surgical resection was made by multidisciplinary team. The second tumor was confirmed to be IAF with size of 17 cm × 13 cm × 11 cm. Although IAF subsequent to GIST is very rare, it is of clinical significance in imatinib era as an influencing factor for making clinical decision. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1076715989961803
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spelling pubmed-37510732013-08-24 Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor Jiang, Dongxian He, Deming Hou, Yingyong Lu, Weiqi Shi, Yuan Hu, Qin Lu, Shaohua Xu, Chen Liu, Yalan Liu, Ju Tan, Yunshan Zhu, Xiongzeng Diagn Pathol Case Report ABSTRACT: Intra-abdominal fibromatosis (IAF) commonly develops in patients who had abdominal surgery. In rare instances, it occurs subsequent to gastrointestinal stromal tumor (GIST). This special situation has clinical significance in imatinib era. About 1000 patients with GIST in our institution from 1993 to 2010 were re-evaluated based on their clinical and pathological data, the treatment strategies and the follow-up information. We identified 2 patients who developed IAF after GIST resection. Patient 1 was a 54 year-old male and had 5 cm × 4.5 cm × 3.5 cm jejunal GIST excised on February 22, 1994. Three years later, an abdominal mass with 7 cm × 6 cm × 3 cm was identified. He was diagnosed as recurrent GIST from clinical point of view. After excision, the second tumor was confirmed to be IAF. Patient 2 was a 45-year-old male and had 6 cm × 4 cm × 3 cm duodenal GIST excised on August 19, 2008. One year later, a 4 cm mass was found at the original surgical site. The patient refused to take imatinib until the tumor increased to 8 cm six months later. The tumor continued to increase after 6 months’ imatinib therapy, decision of surgical resection was made by multidisciplinary team. The second tumor was confirmed to be IAF with size of 17 cm × 13 cm × 11 cm. Although IAF subsequent to GIST is very rare, it is of clinical significance in imatinib era as an influencing factor for making clinical decision. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1076715989961803 BioMed Central 2013-07-31 /pmc/articles/PMC3751073/ /pubmed/23902675 http://dx.doi.org/10.1186/1746-1596-8-125 Text en Copyright © 2013 Jiang et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jiang, Dongxian
He, Deming
Hou, Yingyong
Lu, Weiqi
Shi, Yuan
Hu, Qin
Lu, Shaohua
Xu, Chen
Liu, Yalan
Liu, Ju
Tan, Yunshan
Zhu, Xiongzeng
Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor
title Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor
title_full Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor
title_fullStr Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor
title_full_unstemmed Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor
title_short Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor
title_sort subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751073/
https://www.ncbi.nlm.nih.gov/pubmed/23902675
http://dx.doi.org/10.1186/1746-1596-8-125
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