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5-HT(2C)R blockade in the amygdala conveys analgesic efficacy to SSRIs in a rat model of arthritis pain
BACKGROUND: Pain, including arthritic pain, has a negative affective component and is often associated with anxiety and depression. However, selective serotonin reuptake inhibitor antidepressants (SSRIs) show limited effectiveness in pain. The amygdala plays a key role in the emotional-affective com...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751088/ https://www.ncbi.nlm.nih.gov/pubmed/23937887 http://dx.doi.org/10.1186/1744-8069-9-41 |