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Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors
BACKGROUND: Cisplatin (CDDP) resistance in testicular germ cell tumors (GCTs) is still a clinical challenge, and one associated with poor prognosis. The purpose of this work was to test pazopanib, an anti-tumoral and anti-angiogenic multikinase inhibitor, and its combination with lapatinib (an anti-...
Autores principales: | Juliachs, Mercè, Vidal, August, del Muro, Xavier Garcia, Piulats, Josep M, Condom, Enric, Casanovas, Oriol, Graupera, Mariona, Germà, Jose R, Villanueva, Alberto, Viñals, Francesc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751347/ https://www.ncbi.nlm.nih.gov/pubmed/23937707 http://dx.doi.org/10.1186/1471-2407-13-382 |
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