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Evaluation of the need for routine clinical testing of PALB2 c.1592delT mutation in BRCA negative Northern Finnish breast cancer families
BACKGROUND: Testing for mutations in the BRCA1 and BRCA2 genes among high-risk breast cancer patients has become a routine practice among clinical geneticists. Unfortunately, however, the genetic background of a majority of the cases coming to the clinics remains currently unexplained, making geneti...
Autores principales: | Haanpää, Maria, Pylkäs, Katri, Moilanen, Jukka S, Winqvist, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751431/ https://www.ncbi.nlm.nih.gov/pubmed/23941127 http://dx.doi.org/10.1186/1471-2350-14-82 |
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