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Effects of lovastatin treatment on the metabolic distributions in the Han:SPRD rat model of polycystic kidney disease

BACKGROUND: We previously demonstrated that lovastatin decreases cyst volume and improves kidney function in the Han:SPRD (Cy/+) rat model of ADPKD. Since endothelial dysfunction and inflammatory activity are evident in patients with ADPKD, we investigated whether lovastatin reduces the inflammation...

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Detalles Bibliográficos
Autores principales:	Klawitter, Jelena, Zafar, Iram, Klawitter, Jost, Pennington, Alexander T, Klepacki, Jacek, Gitomer, Berenice Y, Schrier, Robert W, Christians, Uwe, Edelstein, Charles L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751441/ https://www.ncbi.nlm.nih.gov/pubmed/23902712 http://dx.doi.org/10.1186/1471-2369-14-165

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