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8-hydroxy-2′-deoxyguanosine in colorectal adenocarcinoma – is it a result of oxidative stress?

BACKGROUND: 8-hydroxy-2′-deoxyguanosine (8-OHdG) is one of the most abundant oxidatively modified lesions in DNA and is a marker of the oxidative stress. 8-OHdG is a mutagenic lesion and it can mispair with adenine, causing G: C→T: A transversion. Our task was to determine the 8-OHdG level in patien...

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Detalles Bibliográficos
Autores principales:	Płachetka, Anna, Adamek, Brygida, Strzelczyk, Joanna K., Krakowczyk, Łukasz, Migula, Paweł, Nowak, Przemysław, Wiczkowski, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2013
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751519/ https://www.ncbi.nlm.nih.gov/pubmed/23963109 http://dx.doi.org/10.12659/MSM.883999

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