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Identification of the feline foamy virus Bet domain essential for APOBEC3 counteraction

BACKGROUND: APOBEC3 (A3) proteins restrict viral replication by cytidine deamination of viral DNA genomes and impairing reverse transcription and integration. To escape this restriction, lentiviruses have evolved the viral infectivity factor (Vif), which binds A3 proteins and targets them for proteo...

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Detalles Bibliográficos
Autores principales: Lukic, Dragana Slavkovic, Hotz-Wagenblatt, Agnes, Lei, Janet, Räthe, Ann-Mareen, Mühle, Michael, Denner, Joachim, Münk, Carsten, Löchelt, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751544/
https://www.ncbi.nlm.nih.gov/pubmed/23880220
http://dx.doi.org/10.1186/1742-4690-10-76

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