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The role of indoleamine 2,3-dioxygenase in LP-BPM5 murine retroviral disease progression
BACKGROUND: Indoleamine 2,3-dioxygenase (IDO) is an immunomodulatory intracellular enzyme involved in tryptophan degradation. IDO is induced during cancer and microbial infections by cytokines, ligation of co-stimulatory molecules and/or activation of pattern recognition receptors, ultimately leadin...
Autores principales: | O’Connor, Megan A, Green, William R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751850/ https://www.ncbi.nlm.nih.gov/pubmed/23680027 http://dx.doi.org/10.1186/1743-422X-10-154 |
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