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Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic Leukemia
Progranulin (Pgrn) is a 88 kDa secreted protein with pleiotropic functions including regulation of cell cycle progression, cell motility, wound repair and tumorigenesis. Using microarray based gene expression profiling we have recently demonstrated that the gene for Pgrn, granulin (GRN), is signific...
Autores principales: | Göbel, Maria, Eisele, Lewin, Möllmann, Michael, Hüttmann, Andreas, Johansson, Patricia, Scholtysik, René, Bergmann, Manuela, Busch, Raymonde, Döhner, Hartmut, Hallek, Michael, Seiler, Till, Stilgenbauer, Stephan, Klein-Hitpass, Ludger, Dührsen, Ulrich, Dürig, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751910/ https://www.ncbi.nlm.nih.gov/pubmed/24009671 http://dx.doi.org/10.1371/journal.pone.0072107 |
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