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Variable Behavior of iPSCs Derived from CML Patients for Response to TKI and Hematopoietic Differentiation
Chronic myeloid leukemia disease (CML) found effective therapy by treating patients with tyrosine kinase inhibitors (TKI), which suppress the BCR-ABL1 oncogene activity. However, the majority of patients achieving remission with TKI still have molecular evidences of disease persistence. Various mech...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751925/ https://www.ncbi.nlm.nih.gov/pubmed/24058405 http://dx.doi.org/10.1371/journal.pone.0071596 |