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Programmatically Selected Multidrug-Resistant Strains Drive the Emergence of Extensively Drug-Resistant Tuberculosis in South Africa

BACKGROUND: South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included ofloxacin, kanamycin, ethionamide...

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Detalles Bibliográficos
Autores principales:	Müller, Borna, Chihota, Violet N., Pillay, Manormoney, Klopper, Marisa, Streicher, Elizabeth M., Coetzee, Gerrit, Trollip, Andre, Hayes, Cindy, Bosman, Marlein E., Gey van Pittius, Nicolaas C., Victor, Thomas C., Gagneux, Sebastien, van Helden, Paul D., Warren, Robin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751934/ https://www.ncbi.nlm.nih.gov/pubmed/24058399 http://dx.doi.org/10.1371/journal.pone.0070919

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