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The combination of two Sle2 lupus-susceptibility loci and Cdkn2c deficiency leads to T cell-mediated pathology in B6.Fas(lpr) mice
The NZM2410 Sle2c1 lupus susceptibility locus is responsible for the expansion of the B1a cell compartment and for the induction of T-cell induced renal and skin pathology on a CD95 deficient (Fas(lpr))-background. We have previously shown that deficiency in cyclin-dependent kinase inhibitor p18(INK...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752316/ https://www.ncbi.nlm.nih.gov/pubmed/23698709 http://dx.doi.org/10.1038/gene.2013.28 |