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Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
Even though highly active anti-retroviral therapy is able to keep HIV-1 replication under control, the virus can lie in a dormant state within the host genome, known as a latent reservoir, and poses a threat to re-emerge at any time. However, novel technologies aimed at disrupting HIV-1 provirus may...
Autores principales: | Ebina, Hirotaka, Misawa, Naoko, Kanemura, Yuka, Koyanagi, Yoshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752613/ https://www.ncbi.nlm.nih.gov/pubmed/23974631 http://dx.doi.org/10.1038/srep02510 |
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