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Critical evaluation of biodegradable polymers used in nanodrugs

Use of biodegradable polymers for biomedical applications has increased in recent decades due to their biocompatibility, biodegradability, flexibility, and minimal side effects. Applications of these materials include creation of skin, blood vessels, cartilage scaffolds, and nanosystems for drug del...

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Detalles Bibliográficos
Autores principales: Marin, Edgar, Briceño, Maria Isabel, Caballero-George, Catherina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753153/
https://www.ncbi.nlm.nih.gov/pubmed/23990720
http://dx.doi.org/10.2147/IJN.S47186
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author Marin, Edgar
Briceño, Maria Isabel
Caballero-George, Catherina
author_facet Marin, Edgar
Briceño, Maria Isabel
Caballero-George, Catherina
author_sort Marin, Edgar
collection PubMed
description Use of biodegradable polymers for biomedical applications has increased in recent decades due to their biocompatibility, biodegradability, flexibility, and minimal side effects. Applications of these materials include creation of skin, blood vessels, cartilage scaffolds, and nanosystems for drug delivery. These biodegradable polymeric nanoparticles enhance properties such as bioavailability and stability, and provide controlled release of bioactive compounds. This review evaluates the classification, synthesis, degradation mechanisms, and biological applications of the biodegradable polymers currently being studied as drug delivery carriers. In addition, the use of nanosystems to solve current drug delivery problems are reviewed.
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spelling pubmed-37531532013-08-29 Critical evaluation of biodegradable polymers used in nanodrugs Marin, Edgar Briceño, Maria Isabel Caballero-George, Catherina Int J Nanomedicine Review Use of biodegradable polymers for biomedical applications has increased in recent decades due to their biocompatibility, biodegradability, flexibility, and minimal side effects. Applications of these materials include creation of skin, blood vessels, cartilage scaffolds, and nanosystems for drug delivery. These biodegradable polymeric nanoparticles enhance properties such as bioavailability and stability, and provide controlled release of bioactive compounds. This review evaluates the classification, synthesis, degradation mechanisms, and biological applications of the biodegradable polymers currently being studied as drug delivery carriers. In addition, the use of nanosystems to solve current drug delivery problems are reviewed. Dove Medical Press 2013 2013-08-19 /pmc/articles/PMC3753153/ /pubmed/23990720 http://dx.doi.org/10.2147/IJN.S47186 Text en © 2013 Marin et al. This work is published by Dove Medical Press Ltd, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Ltd, provided the work is properly attributed.
spellingShingle Review
Marin, Edgar
Briceño, Maria Isabel
Caballero-George, Catherina
Critical evaluation of biodegradable polymers used in nanodrugs
title Critical evaluation of biodegradable polymers used in nanodrugs
title_full Critical evaluation of biodegradable polymers used in nanodrugs
title_fullStr Critical evaluation of biodegradable polymers used in nanodrugs
title_full_unstemmed Critical evaluation of biodegradable polymers used in nanodrugs
title_short Critical evaluation of biodegradable polymers used in nanodrugs
title_sort critical evaluation of biodegradable polymers used in nanodrugs
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753153/
https://www.ncbi.nlm.nih.gov/pubmed/23990720
http://dx.doi.org/10.2147/IJN.S47186
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