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Intronic Splicing Enhancers, Cognate Splicing Factors and Context Dependent Regulation Rules
Most human genes produce multiple splicing isoforms with distinct functions. To systematically understand splicing regulation, we conducted an unbiased screen and identified >100 intronic splicing enhancers (ISEs) that were clustered by sequence similarity into six groups. All ISEs functioned in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753194/ https://www.ncbi.nlm.nih.gov/pubmed/22983564 http://dx.doi.org/10.1038/nsmb.2377 |