MicroRNA-34a Mediates the Autocrine Signaling of PAR(2)-Activating Proteinase and Its Role in Colonic Cancer Cell Proliferation

The tumor microenvironment is replete with proteinases. As a sensor of proteinases, proteinase activated receptor 2 (PAR(2)) plays critical roles in tumorigenesis. We showed that PAR(2) and its activating proteinase were coexpressed in different colon cancer cell lines, including HT29. Inactivating...

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Detalles Bibliográficos
Autores principales: Ma, Yiming, Bao-Han, Wuyun, Lv, Xue, Su, Yuntao, Zhao, Xinhua, Yin, Yongmei, Zhang, Xingmao, Zhou, Zhixiang, MacNaughton, Wallace K., Wang, Hongying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753253/
https://www.ncbi.nlm.nih.gov/pubmed/23991105
http://dx.doi.org/10.1371/journal.pone.0072383

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