Ex-Vivo Dynamic 3-D Culture of Human Tissues in the RCCS™ Bioreactor Allows the Study of Multiple Myeloma Biology and Response to Therapy

Three-dimensional (3-D) culture models are emerging as invaluable tools in tumor biology, since they reproduce tissue-specific structural features and cell-cell interactions more accurately than conventional 2-D cultures. Multiple Myeloma, which depends on myeloma cell-Bone Marrow microenvironment i...

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Detalles Bibliográficos
Autores principales: Ferrarini, Marina, Steimberg, Nathalie, Ponzoni, Maurilio, Belloni, Daniela, Berenzi, Angiola, Girlanda, Stefania, Caligaris-Cappio, Federico, Mazzoleni, Giovanna, Ferrero, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753321/
https://www.ncbi.nlm.nih.gov/pubmed/23990965
http://dx.doi.org/10.1371/journal.pone.0071613

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