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Bmp7 Maintains Undifferentiated Kidney Progenitor Population and Determines Nephron Numbers at Birth

The number of nephrons, the functional units of the kidney, varies among individuals. A low nephron number at birth is associated with a risk of hypertension and the progression of renal insufficiency. The molecular mechanisms determining nephron number during embryogenesis have not yet been clarifi...

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Detalles Bibliográficos
Autores principales: Tomita, Mayumi, Asada, Misako, Asada, Nariaki, Nakamura, Jin, Oguchi, Akiko, Higashi, Atsuko Y., Endo, Shuichiro, Robertson, Elizabeth, Kimura, Takeshi, Kita, Toru, Economides, Aris N., Kreidberg, Jordan, Yanagita, Motoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753328/
https://www.ncbi.nlm.nih.gov/pubmed/23991197
http://dx.doi.org/10.1371/journal.pone.0073554

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