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Generation of a Mouse Model with Down-Regulated U50 snoRNA (SNORD50) Expression and Its Organ-Specific Phenotypic Modulation
Box C/D-type small nucleolar RNAs (snoRNAs) are functional RNAs responsible for mediating 2′-O-ribose methylation of ribosomal RNAs (rRNAs) within the nucleolus. In the past years, evidence for the involvement of human U50 snoRNA in tumorigenesis has been accumulating. We previously identified U50HG...
Autores principales: | Soeno, Yuuichi, Fujita, Kazuya, Kudo, Tomoo, Asagiri, Masataka, Kakuta, Shigeru, Taya, Yuji, Shimazu, Yoshihito, Sato, Kaori, Tanaka-Fujita, Ritsuko, Kubo, Sachiko, Iwakura, Yoichiro, Nakamura, Yoshikazu, Mori, Shigeo, Aoba, Takaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753356/ https://www.ncbi.nlm.nih.gov/pubmed/23991050 http://dx.doi.org/10.1371/journal.pone.0072105 |
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