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A probabilistic approach to learn chromatin architecture and accurate inference of the NF-κB/RelA regulatory network using ChIP-Seq
Using nuclear factor-κB (NF-κB) ChIP-Seq data, we present a framework for iterative learning of regulatory networks. For every possible transcription factor-binding site (TFBS)-putatively regulated gene pair, the relative distance and orientation are calculated to learn which TFBSs are most likely t...
Autores principales: | Yang, Jun, Mitra, Abhishek, Dojer, Norbert, Fu, Shuhua, Rowicka, Maga, Brasier, Allan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753626/ https://www.ncbi.nlm.nih.gov/pubmed/23771139 http://dx.doi.org/10.1093/nar/gkt493 |
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