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Inhibition of DNA damage repair by artificial activation of PARP with siDNA

One of the major early steps of repair is the recruitment of repair proteins at the damage site, and this is coordinated by a cascade of modifications controlled by phosphatidylinositol 3-kinase-related kinases and/or poly (ADP-ribose) polymerase (PARP). We used short interfering DNA molecules mimic...

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Detalles Bibliográficos
Autores principales:	Croset, Amelie, Cordelières, Fabrice P., Berthault, Nathalie, Buhler, Cyril, Sun, Jian-Sheng, Quanz, Maria, Dutreix, Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753643/ https://www.ncbi.nlm.nih.gov/pubmed/23761435 http://dx.doi.org/10.1093/nar/gkt522

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