Multiplexed Microcolumn-Based Process for Efficient Selection of RNA Aptamers

[Image: see text] We describe a reusable microcolumn and process for the efficient discovery of nucleic acid aptamers for multiple target molecules. The design of our device requires only microliter volumes of affinity chromatography resin—a condition that maximizes the enrichment of target-binding...

Descripción completa

Detalles Bibliográficos
Autores principales: Latulippe, David R., Szeto, Kylan, Ozer, Abdullah, Duarte, Fabiana M., Kelly, Christopher V., Pagano, John M., White, Brian S., Shalloway, David, Lis, John T., Craighead, Harold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753675/
https://www.ncbi.nlm.nih.gov/pubmed/23398198
http://dx.doi.org/10.1021/ac400105e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753675/
https://www.ncbi.nlm.nih.gov/pubmed/23398198
http://dx.doi.org/10.1021/ac400105e

Ejemplares similares