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HMGN1 Modulates Nucleosome Occupancy and DNase I Hypersensitivity at the CpG Island Promoters of Embryonic Stem Cells

Chromatin structure plays a key role in regulating gene expression and embryonic differentiation; however, the factors that determine the organization of chromatin around regulatory sites are not fully known. Here we show that HMGN1, a nucleosome-binding protein ubiquitously expressed in vertebrate...

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Detalles Bibliográficos
Autores principales: Deng, Tao, Zhu, Z. Iris, Zhang, Shaofei, Leng, Fenfei, Cherukuri, Srujana, Hansen, Loren, Mariño-Ramírez, Leonardo, Meshorer, Eran, Landsman, David, Bustin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753902/
https://www.ncbi.nlm.nih.gov/pubmed/23775126
http://dx.doi.org/10.1128/MCB.00435-13