Epigenetic Functions of Smchd1 Repress Gene Clusters on the Inactive X Chromosome and on Autosomes

The Smchd1 gene encodes a large protein with homology to the SMC family of proteins involved in chromosome condensation and cohesion. Previous studies have found that Smchd1 has an important role in CpG island (CGI) methylation on the inactive X chromosome (Xi) and in stable silencing of some Xi gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Gendrel, Anne-Valerie, Tang, Y. Amy, Suzuki, Masako, Godwin, Jonathan, Nesterova, Tatyana B., Greally, John M., Heard, Edith, Brockdorff, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753908/
https://www.ncbi.nlm.nih.gov/pubmed/23754746
http://dx.doi.org/10.1128/MCB.00145-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753908/
https://www.ncbi.nlm.nih.gov/pubmed/23754746
http://dx.doi.org/10.1128/MCB.00145-13

Ejemplares similares