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Computational detection of abundant long-range nucleotide covariation in Drosophila genomes
Functionally important nucleotide base-pairing often manifests itself in sequence alignments in the form of compensatory base changes (covariation). We developed a novel index-based computational method (CovaRNA) to detect long-range covariation on a genomic scale, as well as another computational m...
Autores principales: | Bindewald, Eckart, Shapiro, Bruce A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753924/ https://www.ncbi.nlm.nih.gov/pubmed/23887147 http://dx.doi.org/10.1261/rna.037630.112 |
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