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Conservation of structure and mechanism by Trm5 enzymes
Enzymes of the Trm5 family catalyze methyl transfer from S-adenosyl methionine (AdoMet) to the N(1) of G37 to synthesize m(1)G37-tRNA as a critical determinant to prevent ribosome frameshift errors. Trm5 is specific to eukaryotes and archaea, and it is unrelated in evolution from the bacterial count...
Autores principales: | Christian, Thomas, Gamper, Howard, Hou, Ya-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753926/ https://www.ncbi.nlm.nih.gov/pubmed/23887145 http://dx.doi.org/10.1261/rna.039503.113 |
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