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Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA

The bacteriophage phi29 DNA packaging motor, one of the strongest biological motors characterized to date, is geared by a packaging RNA (pRNA) ring. When assembled from three RNA fragments, its three-way junction (3WJ) motif is highly thermostable, is resistant to 8 M urea, and remains associated at...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Endrizzi, James A., Shu, Yi, Haque, Farzin, Sauter, Claude, Shlyakhtenko, Lyudmila S., Lyubchenko, Yuri, Guo, Peixuan, Chi, Young-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753930/
https://www.ncbi.nlm.nih.gov/pubmed/23884902
http://dx.doi.org/10.1261/rna.037077.112