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Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA
The bacteriophage phi29 DNA packaging motor, one of the strongest biological motors characterized to date, is geared by a packaging RNA (pRNA) ring. When assembled from three RNA fragments, its three-way junction (3WJ) motif is highly thermostable, is resistant to 8 M urea, and remains associated at...
Autores principales: | Zhang, Hui, Endrizzi, James A., Shu, Yi, Haque, Farzin, Sauter, Claude, Shlyakhtenko, Lyudmila S., Lyubchenko, Yuri, Guo, Peixuan, Chi, Young-In |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753930/ https://www.ncbi.nlm.nih.gov/pubmed/23884902 http://dx.doi.org/10.1261/rna.037077.112 |
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