General aspects of drug interactions with systemic antifungals in a retrospective study sample*

A retrospective study evaluating hepatic laboratory alterations and potential drug interactions in patients treated for onychomycosis. We evaluated 202 patients, 82% female. In 273 liver enzyme tests, there were changes in only 6%. Potential drug interactions were identified in 28% of patients for i...

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Detalles Bibliográficos
Autores principales: Schmitt, Juliano Vilaverde, Bombonatto, Giovana, Trierweiler, Stella Maris, Fabri, Andrea Buosi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2013
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754391/
https://www.ncbi.nlm.nih.gov/pubmed/23793213
http://dx.doi.org/10.1590/abd1806-4841.20131781
Descripción
Sumario:A retrospective study evaluating hepatic laboratory alterations and potential drug interactions in patients treated for onychomycosis. We evaluated 202 patients, 82% female. In 273 liver enzyme tests, there were changes in only 6%. Potential drug interactions were identified in 28% of patients for imidazole and 14% for terbinafine. The risk of potential interactions increased with the patient's age and use of multiple drugs.

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