General aspects of drug interactions with systemic antifungals in a retrospective study sample*

A retrospective study evaluating hepatic laboratory alterations and potential drug interactions in patients treated for onychomycosis. We evaluated 202 patients, 82% female. In 273 liver enzyme tests, there were changes in only 6%. Potential drug interactions were identified in 28% of patients for i...

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Detalles Bibliográficos
Autores principales: Schmitt, Juliano Vilaverde, Bombonatto, Giovana, Trierweiler, Stella Maris, Fabri, Andrea Buosi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2013
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754391/
https://www.ncbi.nlm.nih.gov/pubmed/23793213
http://dx.doi.org/10.1590/abd1806-4841.20131781
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author Schmitt, Juliano Vilaverde
Bombonatto, Giovana
Trierweiler, Stella Maris
Fabri, Andrea Buosi
author_facet Schmitt, Juliano Vilaverde
Bombonatto, Giovana
Trierweiler, Stella Maris
Fabri, Andrea Buosi
author_sort Schmitt, Juliano Vilaverde
collection PubMed
description A retrospective study evaluating hepatic laboratory alterations and potential drug interactions in patients treated for onychomycosis. We evaluated 202 patients, 82% female. In 273 liver enzyme tests, there were changes in only 6%. Potential drug interactions were identified in 28% of patients for imidazole and 14% for terbinafine. The risk of potential interactions increased with the patient's age and use of multiple drugs.
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spelling pubmed-37543912013-09-16 General aspects of drug interactions with systemic antifungals in a retrospective study sample* Schmitt, Juliano Vilaverde Bombonatto, Giovana Trierweiler, Stella Maris Fabri, Andrea Buosi An Bras Dermatol Communication A retrospective study evaluating hepatic laboratory alterations and potential drug interactions in patients treated for onychomycosis. We evaluated 202 patients, 82% female. In 273 liver enzyme tests, there were changes in only 6%. Potential drug interactions were identified in 28% of patients for imidazole and 14% for terbinafine. The risk of potential interactions increased with the patient's age and use of multiple drugs. Sociedade Brasileira de Dermatologia 2013 /pmc/articles/PMC3754391/ /pubmed/23793213 http://dx.doi.org/10.1590/abd1806-4841.20131781 Text en ©2013 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communication
Schmitt, Juliano Vilaverde
Bombonatto, Giovana
Trierweiler, Stella Maris
Fabri, Andrea Buosi
General aspects of drug interactions with systemic antifungals in a retrospective study sample*
title General aspects of drug interactions with systemic antifungals in a retrospective study sample*
title_full General aspects of drug interactions with systemic antifungals in a retrospective study sample*
title_fullStr General aspects of drug interactions with systemic antifungals in a retrospective study sample*
title_full_unstemmed General aspects of drug interactions with systemic antifungals in a retrospective study sample*
title_short General aspects of drug interactions with systemic antifungals in a retrospective study sample*
title_sort general aspects of drug interactions with systemic antifungals in a retrospective study sample*
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754391/
https://www.ncbi.nlm.nih.gov/pubmed/23793213
http://dx.doi.org/10.1590/abd1806-4841.20131781
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