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Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the people’s Republic of China

The reported number of registered leprosy patients worldwide declined with the introduction of multidrug therapy. However, the emergence of rifampicin resistance in leprosy patients engenders difficulties for an individual patient, and its dissemination could pose a threat to leprosy control. This s...

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Detalles Bibliográficos
Autores principales: Yu, Meiwen, Wu, Kan, Pei, Bing, Yang, Degang, Wang, Qiulin, Wang, Hongsheng, Shen, Jianping, Yan, Liangbing, Zhang, Guochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754489/
https://www.ncbi.nlm.nih.gov/pubmed/23986632
http://dx.doi.org/10.2147/CIA.S49653
Descripción
Sumario:The reported number of registered leprosy patients worldwide declined with the introduction of multidrug therapy. However, the emergence of rifampicin resistance in leprosy patients engenders difficulties for an individual patient, and its dissemination could pose a threat to leprosy control. This study reports an elderly patient who was diagnosed with rifampicin-resistant lepromatous leprosy. This case indicates that inadequate treatment and poor compliance may eventually result in rifampicin resistance in Mycobacterium leprae and clinical relapse.