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Non-enzymatic glycosylation of a type I collagen matrix: effects on osteoblastic development and oxidative stress
BACKGROUND: The tissue accumulation of protein-bound advanced glycation endproducts (AGE) may be involved in the etiology of diabetic chronic complications, including osteopenia. The aim of this study was to investigate the effect of an AGE-modified type I collagen substratum on the adhesion, spread...
Autores principales: | McCarthy, Antonio D, Etcheverry, Susana B, Bruzzone, Liliana, Lettieri, Gabriela, Barrio, Daniel A, Cortizo, Ana M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC37548/ https://www.ncbi.nlm.nih.gov/pubmed/11518540 http://dx.doi.org/10.1186/1471-2121-2-16 |
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