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The CK2 Kinase Stabilizes CLOCK and Represses Its Activity in the Drosophila Circadian Oscillator

Phosphorylation is a pivotal regulatory mechanism for protein stability and activity in circadian clocks regardless of their evolutionary origin. It determines the speed and strength of molecular oscillations by acting on transcriptional activators and their repressors, which form negative feedback...

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Detalles Bibliográficos
Autores principales: Szabó, Áron, Papin, Christian, Zorn, Daniela, Ponien, Prishila, Weber, Frank, Raabe, Thomas, Rouyer, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754892/
https://www.ncbi.nlm.nih.gov/pubmed/24013921
http://dx.doi.org/10.1371/journal.pbio.1001645