Cargando…
Both PAX4 and MAFA Are Expressed in a Substantial Proportion of Normal Human Pancreatic Alpha Cells and Deregulated in Patients with Type 2 Diabetes
Pax4 and MafA (v-maf musculoaponeurotic fibrosarcoma oncogene homolog A) are two transcription factors crucial for normal functions of islet beta cells in the mouse. Intriguingly, recent studies indicate the existence of notable difference between human and rodent islet in terms of gene expression a...
Autores principales: | Bonnavion, Rémy, Jaafar, Rami, Kerr-Conte, Julie, Assade, Fouzia, van Stralen, Esther, Leteurtre, Emmanuelle, Pouponnot, Célio, Gargani, Sofia, Pattou, François, Bertolino, Philippe, Cordier-Bussat, Martine, Lu, Jieli, Zhang, Chang Xian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754968/ https://www.ncbi.nlm.nih.gov/pubmed/24013263 http://dx.doi.org/10.1371/journal.pone.0072194 |
Ejemplares similares
-
Mafa-dependent GABAergic activity promotes mouse neonatal apneas
por: Lecoin, Laure, et al.
Publicado: (2022) -
Comprehensive identification of high-frequency and co-occurring Mafa-B, Mafa-DQB1, and Mafa-DRB alleles in cynomolgus macaques of Vietnamese origin
por: Ling, Fei, et al.
Publicado: (2012) -
Pax4 synergistically acts with Pdx1, Ngn3 and MafA to induce HuMSCs to differentiate into functional pancreatic β-cells
por: Zhang, Ting, et al.
Publicado: (2019) -
The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids
por: Fu, Jingyuan, et al.
Publicado: (2015) -
NRAS-driven melanoma: A RAF can hide another
por: Druillennec, Sabine, et al.
Publicado: (2017)