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Mycoplasma fermentans Inhibits the Activity of Cellular DNA Topoisomerase I by Activation of PARP1 and Alters the Efficacy of Its Anti-Cancer Inhibitor

To understand the effects of the interaction between Mycoplasma and cells on the host cellular function, it is important to elucidate the influences of infection of cells with Mycoplasma on nuclear enzymes such as DNA Topoisomerase type I (Topo I). Human Topo I participates in DNA transaction proces...

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Detalles Bibliográficos
Autores principales: Afriat, Reuven, Horowitz, Shulamith, Priel, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754970/
https://www.ncbi.nlm.nih.gov/pubmed/24013388
http://dx.doi.org/10.1371/journal.pone.0072377

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