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Elucidating the Signal Responses of Multi-Parametric Surface Plasmon Resonance Living Cell Sensing: A Comparison between Optical Modeling and Drug–MDCKII Cell Interaction Measurements
In vitro cell-based assays are widely used during the drug discovery and development process to test the biological activity of new drugs. Most of the commonly used cell-based assays, however, lack the ability to measure in real-time or under dynamic conditions (e.g. constant flow). In this study a...
Autores principales: | Viitala, Tapani, Granqvist, Niko, Hallila, Susanna, Raviña, Manuela, Yliperttula, Marjo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754984/ https://www.ncbi.nlm.nih.gov/pubmed/24015218 http://dx.doi.org/10.1371/journal.pone.0072192 |
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