The multi zinc-finger protein Trps1 acts as a regulator of histone deacetylation during mitosis

TRPS1, the gene mutated in human "Tricho-Rhino-Phalangeal syndrome," encodes a multi zinc-finger nuclear regulator of chondrocyte proliferation and differentiation. Here, we have identified a new function of Trps1 in controlling mitotic progression in chondrocytes. Loss of Trps1 in mice le...

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Detalles Bibliográficos
Autores principales: Wuelling, Manuela, Pasdziernik, Markus, Moll, Carina N, Thiesen, Andrea M, Schneider, Sabine, Johannes, Christian, Vortkamp, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755072/
https://www.ncbi.nlm.nih.gov/pubmed/23892436
http://dx.doi.org/10.4161/cc.25267

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