Cargando…

CUL3 and protein kinases: Insights from PLK1/KLHL22 interaction

Posttranslational mechanisms drive fidelity of cellular processes. Phosphorylation and ubiquitination of substrates represent very common, covalent, posttranslational modifications and are often co-regulated. Phosphorylation may play a critical role both by directly regulating E3-ubiquitin ligases a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Metzger, Thibaud, Kleiss, Charlotte, Sumara, Izabela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755079/ https://www.ncbi.nlm.nih.gov/pubmed/24067371 http://dx.doi.org/10.4161/cc.25369

Ejemplares similares

The Cul3–KLHL21 E3 ubiquitin ligase targets Aurora B to midzone microtubules in anaphase and is required for cytokinesis
por: Maerki, Sarah, et al.
Publicado: (2009)

Regulating PLK1 dynamics by Cullin3/KLHL22-mediated ubiquitylation
por: Beck, Jochen, et al.
Publicado: (2013)

A synthetic KLHL20 ligand to validate CUL3(KLHL20) as a potent E3 ligase for targeted protein degradation
por: Farrell, Brian M., et al.
Publicado: (2022)

UBAP2L‐dependent coupling of PLK1 localization and stability during mitosis
por: Guerber, Lucile, et al.
Publicado: (2023)

The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A
por: Moghe, Saili, et al.
Publicado: (2011)

KLHL12 can form large COPII structures in the absence of CUL3 neddylation
por: Moretti, Tamara, et al.
Publicado: (2023)

The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction
por: Ohta, Akihito, et al.
Publicado: (2013)

Cul3-KLHL20 ubiquitin ligase: physiological functions, stress responses, and disease implications
por: Chen, Hsin-Yi, et al.
Publicado: (2016)

Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome)
por: Glover, Mark, et al.
Publicado: (2014)

Molecular dynamics of PLK1 during mitosis
por: Schmucker, Stephane, et al.
Publicado: (2014)

Cortical dynamics during cell motility are regulated by CRL3(KLHL21) E3 ubiquitin ligase
por: Courtheoux, Thibault, et al.
Publicado: (2016)

ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation
por: Tian, Miaomiao, et al.
Publicado: (2021)

Corrigendum: Cortical dynamics during cell motility are regulated by CRL3(KLHL21) E3 ubiquitin ligase
por: Courtheoux, Thibault, et al.
Publicado: (2016)

Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation
por: Schumacher, Frances-Rose, et al.
Publicado: (2014)

Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase
por: Chen, Zhuoyao, et al.
Publicado: (2022)

Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction
por: Li, Sunan, et al.
Publicado: (2022)

UBASH3B-mediated silencing of the mitotic checkpoint: Therapeutic perspectives in cancer
por: Krupina, Ksenia, et al.
Publicado: (2017)

Crystal Structure of KLHL3 in Complex with Cullin3
por: Ji, Alan X., et al.
Publicado: (2013)

Overexpression of KLHL23 protein from read‐through transcription of PHOSPHO2‐KLHL23 in gastric cancer increases cell proliferation
por: Choi, Eun‐Seok, et al.
Publicado: (2016)

Clinical Outcome in KLHL24 Cardiomyopathy
por: Vermeer, Mathilde C.S.C., et al.
Publicado: (2023)

Update on the Kelch-like (KLHL) gene family
por: Dhanoa, Bajinder S, et al.
Publicado: (2013)

The Proto-Oncogene Int6 Is Essential for Neddylation of Cul1 and Cul3 in Drosophila
por: Rencus-Lazar, Sigal, et al.
Publicado: (2008)

Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development
por: Kong, Xiangxing, et al.
Publicado: (2022)

Cardiomyopathy with lethal arrhythmias associated with inactivation of KLHL24
por: Hedberg-Oldfors, Carola, et al.
Publicado: (2019)

KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway
por: Song, Yi, et al.
Publicado: (2020)

Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase
por: Chen, Zhuoyao, et al.
Publicado: (2019)

Role of KLHL3 and dietary K(+) in regulating KS-WNK1 expression
por: Ostrosky-Frid, Mauricio, et al.
Publicado: (2021)

Role of Polo-like Kinases Plk1 and Plk4 in the Initiation of Centriole Duplication—Impact on Cancer
por: Hoffmann, Ingrid
Publicado: (2022)

Insights into the diverse mechanisms and effects of variant CUL3-induced familial hyperkalemic hypertension
por: Sharma, Prashant, et al.
Publicado: (2023)

KLHL5 knockdown increases cellular sensitivity to anticancer drugs
por: Schleifer, Robert J., et al.
Publicado: (2018)

KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination
por: Ramirez-Martinez, Andres, et al.
Publicado: (2017)

Epigenetics of Muscle- and Brain-Specific Expression of KLHL Family Genes
por: Ehrlich, Kenneth C., et al.
Publicado: (2020)

Cul-de-sac : roman /
por: Thériault, Yves
Publicado: (1981)

KLHL3 single-nucleotide polymorphism is associated with essential hypertension in Chinese Han population
por: Li, Jin, et al.
Publicado: (2019)

Phosphorylation of PLK3 Is Controlled by Protein Phosphatase 6
por: Aquino Perez, Cecilia, et al.
Publicado: (2020)

Novel Cul3 binding proteins function to remodel E3 ligase complexes
por: Wimuttisuk, Wananit, et al.
Publicado: (2014)

KLHL21, a novel gene that contributes to the progression of hepatocellular carcinoma
por: Shi, Lei, et al.
Publicado: (2016)

New macular findings in individuals with biallelic KLHL7 gene mutation
por: Heng, Ling Zhi, et al.
Publicado: (2019)

The I510V mutation in KLHL10 in a patient with oligoasthenoteratozoospermia
por: HUANG, Zicong, et al.
Publicado: (2021)

KLHL3-dependent WNK4 degradation affected by potassium through the neddylation and autophagy pathway
por: Ying, Siqi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_64c6djesocm6bbas6bt6ba5vmt