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Assessment of clusters of transcription factor binding sites in relationship to human promoter, CpG islands and gene expression

BACKGROUND: Gene expression is regulated mainly by transcription factors (TFs) that interact with regulatory cis-elements on DNA sequences. To identify functional regulatory elements, computer searching can predict TF binding sites (TFBS) using position weight matrices (PWMs) that represent position...

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Detalles Bibliográficos
Autores principales: Murakami, Katsuhiko, Kojima, Toshio, Sakaki, Yoshiyuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC375527/
https://www.ncbi.nlm.nih.gov/pubmed/15053842
http://dx.doi.org/10.1186/1471-2164-5-16