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Assessment of clusters of transcription factor binding sites in relationship to human promoter, CpG islands and gene expression
BACKGROUND: Gene expression is regulated mainly by transcription factors (TFs) that interact with regulatory cis-elements on DNA sequences. To identify functional regulatory elements, computer searching can predict TF binding sites (TFBS) using position weight matrices (PWMs) that represent position...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC375527/ https://www.ncbi.nlm.nih.gov/pubmed/15053842 http://dx.doi.org/10.1186/1471-2164-5-16 |