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Characterization of the complex formed between a potent neutralizing ovine-derived polyclonal anti-TNFα Fab fragment and human TNFα

TNFα (tumour necrosis factor α) is an early mediator in the systemic inflammatory response to infection and is therefore a therapeutic target in sepsis. AZD9773 is an ovine-derived, polyclonal anti-TNFα Fab fragment derived from a pool of serum and currently being developed as a treatment for severe...

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Detalles Bibliográficos
Autores principales:	Abbott, W. Mark, Snow, Melanie, Eckersley, Sonia, Renshaw, Jonathan, Davies, Gareth, Norman, Richard A., Ceuppens, Peter, Slootstra, Jerry, Benschop, Joris J., Hamuro, Yoshitomo, Lee, Jessica E., Newham, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2013
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755337/ https://www.ncbi.nlm.nih.gov/pubmed/23863106 http://dx.doi.org/10.1042/BSR20130044

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