Cargando…

Insulin and GLP-1 infusions demonstrate the onset of adipose-specific insulin resistance in a large fasting mammal: potential glucogenic role for GLP-1

Prolonged food deprivation increases lipid oxidation and utilization, which may contribute to the onset of the insulin resistance associated with fasting. Because insulin resistance promotes the preservation of glucose and oxidation of fat, it has been suggested to be an adaptive response to food de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Viscarra, Jose A, Rodriguez, Ruben, Vazquez-Medina, Jose Pablo, Lee, Andrew, Tift, Michael S, Tavoni, Stephen K, Crocker, Daniel E, Ortiz, Rudy M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755502/ https://www.ncbi.nlm.nih.gov/pubmed/23997935 http://dx.doi.org/10.1002/phy2.23

Ejemplares similares

Counselling Patients for GLP-1 Analogue Therapy: Comparing GLP-1 Analogue with Insulin Counselling
por: Kalra, Sanjay, et al.
Publicado: (2012)

Dissociation of GLP-1 and insulin association with food processing in the brain: GLP-1 sensitivity despite insulin resistance in obese humans
por: Heni, Martin, et al.
Publicado: (2015)

Basal Insulin Use With GLP-1 Receptor Agonists
por: Anderson, Sarah L., et al.
Publicado: (2016)

Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion
por: Ahlkvist, L, et al.
Publicado: (2013)

Differential Stimulation of Insulin Secretion by GLP-1 and Kisspeptin-10
por: Schwetz, Tara A., et al.
Publicado: (2014)

GLP-1 and GLP-2 as Yin and Yang of Intestinal Lipoprotein Production: Evidence for Predominance of GLP-2–Stimulated Postprandial Lipemia in Normal and Insulin-Resistant States
por: Hein, Gustavo J., et al.
Publicado: (2013)

Common Genetic Variation in GLP1R and Insulin Secretion in Response to Exogenous GLP-1 in Nondiabetic Subjects: A pilot study
por: Sathananthan, Airani, et al.
Publicado: (2010)

Effect of Endogenous GLP-1 on Insulin Secretion in Type 2 Diabetes
por: Salehi, Marzieh, et al.
Publicado: (2010)

Longstanding insulin dependent diabetics may not require insulin after the introduction of GLP-1 analogues
por: Raja, Umar Y, et al.
Publicado: (2015)

The Role of Glucagon-Like Peptide 1 (GLP1) in Type 3 Diabetes: GLP-1 Controls Insulin Resistance, Neuroinflammation and Neurogenesis in the Brain
por: Bae, Choon Sang, et al.
Publicado: (2017)

Taking Aim at Islet Hormones With GLP-1: Is Insulin or Glucagon the Better Target?
por: D'Alessio, David A.
Publicado: (2010)

Pancreatic GLP-1r binding potential is reduced in insulin-resistant pigs
por: Malbert, Charles-Henri, et al.
Publicado: (2020)

GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans
por: Hanssen, Ruth, et al.
Publicado: (2021)

Adding GLP-1 Receptor Agonist Therapy to Basal Insulin for Postprandial Glucose Control
por: Rhinehart, Andrew S.
Publicado: (2015)

Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity
por: Shi, Xuemei, et al.
Publicado: (2017)

GLP-1 Improves Adipocyte Insulin Sensitivity Following Induction of Endoplasmic Reticulum Stress
por: Jiang, Yaojing, et al.
Publicado: (2018)

Systematic Synergy of Glucose and GLP-1 to Stimulate Insulin Secretion Revealed by Quantitative Phosphoproteomics
por: Tang, Jia-shu, et al.
Publicado: (2017)

Effect of a GLP-1 mimetic on the insulin response to oral sugar testing in horses
por: Stefanovski, Darko, et al.
Publicado: (2022)

Contribution of GIP and GLP-1 to the Insulin Response to Oral Administration of Glucose in Female Mice
por: Ahrén, Bo
Publicado: (2023)

Loureirin B activates GLP‐1R and promotes insulin secretion in Ins‐1 cells
por: Ding, Yanting, et al.
Publicado: (2020)

DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity
por: Böhm, Anja, et al.
Publicado: (2017)

Combination of basal insulin and GLP-1 receptor agonist: is this the end of basal insulin alone in the treatment of type 2 diabetes?
por: Moreira, Rodrigo Oliveira, et al.
Publicado: (2018)

Purslane Effect on GLP-1 and GLP-1 receptor in type 2 diabetes
por: Heidarzadeh, Sara, et al.
Publicado: (2013)

Allosteric Modulation of the Activity of the Glucagon-like Peptide-1 (GLP-1) Metabolite GLP-1 9–36 Amide at the GLP-1 Receptor
por: Li, Naichang, et al.
Publicado: (2012)

The Antidiabetic Mechanisms of Polyphenols Related to Increased Glucagon-Like Peptide-1 (GLP1) and Insulin Signaling
por: Domínguez Avila, J. Abraham, et al.
Publicado: (2017)

miR-7 Regulates GLP-1-Mediated Insulin Release by Targeting β-Arrestin 1
por: Matarese, Alessandro, et al.
Publicado: (2020)

Combination therapy with GLP-1 receptor agonists and basal insulin: a systematic review of the literature
por: Balena, R, et al.
Publicado: (2013)

Primary-care observational database study of the efficacy of GLP-1 receptor agonists and insulin in the UK
por: Hall, G C, et al.
Publicado: (2013)

Case Study: Use of GLP-1 Receptor Agonist in a Patient on Intensive Insulin Therapy
por: Wiley, Kenneth Calvin, et al.
Publicado: (2015)

GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo
por: Arcones, Alba C., et al.
Publicado: (2021)

Isoprenoid Derivatives of Lysophosphatidylcholines Enhance Insulin and GLP-1 Secretion through Lipid-Binding GPCRs
por: Drzazga, Anna, et al.
Publicado: (2021)

Predictors of Responsiveness to GLP-1 Receptor Agonists in Insulin-Treated Patients with Type 2 Diabetes
por: Gavigan, Colleen, et al.
Publicado: (2023)

Brain GLP‐1 and the regulation of food intake: GLP‐1 action in the brain and its implications for GLP‐1 receptor agonists in obesity treatment
por: Trapp, Stefan, et al.
Publicado: (2021)

Effect of GLP-1/GLP-1R on the Polarization of Macrophages in the Occurrence and Development of Atherosclerosis
por: Yang, Li, et al.
Publicado: (2021)

GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential
por: Ma, Xiaoxuan, et al.
Publicado: (2021)

Combining GLP-1 Receptor Agonists and Basal Insulin in Older Adults with Type 2 Diabetes: Focus on Lixisenatide and Insulin Glargine
por: Handelsman, Yehuda, et al.
Publicado: (2019)

Glucagon, GLP-1 and Thermogenesis
por: González-García, Ismael, et al.
Publicado: (2019)

Glucolipotoxicity and GLP-1 secretion
por: Hong, Jung-Hee, et al.
Publicado: (2021)

GLP-1 and Intestinal Diseases
por: Hunt, Jenna Elizabeth, et al.
Publicado: (2021)

Modeling MEN1 with Patient-Origin iPSCs Reveals GLP-1R Mediated Hypersecretion of Insulin
por: Cheng, Ziqi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2h6r2c08e2vbd3drcda0m5h4n0