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Low-dose CT scan screening for lung cancer: comparison of images and radiation doses between low-dose CT and follow-up standard diagnostic CT

OBJECTIVES: This study aim to compare image quality and radiation doses between low-dose CT and follow-up standard diagnostic CT for lung cancer screening. METHODS: In a single medical institution, 19 subjects who had been screened for lung cancer by low-dose CT before going through follow-up standa...

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Autores principales: Ono, Koji, Hiraoka, Toru, Ono, Asami, Komatsu, Eiji, Shigenaga, Takehiko, Takaki, Hajime, Maeda, Toru, Ogusu, Hiroyuki, Yoshida, Shintaro, Fukushima, Kiyoyasu, Kai, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755805/
https://www.ncbi.nlm.nih.gov/pubmed/24010047
http://dx.doi.org/10.1186/2193-1801-2-393
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author Ono, Koji
Hiraoka, Toru
Ono, Asami
Komatsu, Eiji
Shigenaga, Takehiko
Takaki, Hajime
Maeda, Toru
Ogusu, Hiroyuki
Yoshida, Shintaro
Fukushima, Kiyoyasu
Kai, Michiaki
author_facet Ono, Koji
Hiraoka, Toru
Ono, Asami
Komatsu, Eiji
Shigenaga, Takehiko
Takaki, Hajime
Maeda, Toru
Ogusu, Hiroyuki
Yoshida, Shintaro
Fukushima, Kiyoyasu
Kai, Michiaki
author_sort Ono, Koji
collection PubMed
description OBJECTIVES: This study aim to compare image quality and radiation doses between low-dose CT and follow-up standard diagnostic CT for lung cancer screening. METHODS: In a single medical institution, 19 subjects who had been screened for lung cancer by low-dose CT before going through follow-up standard diagnostic CT were randomly selected. Both CT image sets for all subjects were independently evaluated by five specialized physicians. RESULTS: There were no significant differences between low-dose CT screening and follow-up standard diagnostic CT for lung cancer screening in all 11 criteria. The concordance rate for the diagnoses was approximately 80% (p < 0.001) for all categories. Agreement of the evaluation of all categories in the final diagnosis exceeded 94% (p < 0.001). Five physicians detecting and characterizing the pulmonary nodules did not recognized the difference between low-dose CT screening and follow-up standard diagnostic CT. With low-dose CT, the effective dose ranged between 1.3 and 3.4 mSv, whereas in the follow-up diagnostic CT, the effective dose ranged between 8.5 and 14.0 mSv. CONCLUSION: This study suggests that low-dose CT can be effectively used as a follow-up standard diagnostic CT in place of standard-dose CT in order to reduce the radiation dose.
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spelling pubmed-37558052013-09-04 Low-dose CT scan screening for lung cancer: comparison of images and radiation doses between low-dose CT and follow-up standard diagnostic CT Ono, Koji Hiraoka, Toru Ono, Asami Komatsu, Eiji Shigenaga, Takehiko Takaki, Hajime Maeda, Toru Ogusu, Hiroyuki Yoshida, Shintaro Fukushima, Kiyoyasu Kai, Michiaki Springerplus Research OBJECTIVES: This study aim to compare image quality and radiation doses between low-dose CT and follow-up standard diagnostic CT for lung cancer screening. METHODS: In a single medical institution, 19 subjects who had been screened for lung cancer by low-dose CT before going through follow-up standard diagnostic CT were randomly selected. Both CT image sets for all subjects were independently evaluated by five specialized physicians. RESULTS: There were no significant differences between low-dose CT screening and follow-up standard diagnostic CT for lung cancer screening in all 11 criteria. The concordance rate for the diagnoses was approximately 80% (p < 0.001) for all categories. Agreement of the evaluation of all categories in the final diagnosis exceeded 94% (p < 0.001). Five physicians detecting and characterizing the pulmonary nodules did not recognized the difference between low-dose CT screening and follow-up standard diagnostic CT. With low-dose CT, the effective dose ranged between 1.3 and 3.4 mSv, whereas in the follow-up diagnostic CT, the effective dose ranged between 8.5 and 14.0 mSv. CONCLUSION: This study suggests that low-dose CT can be effectively used as a follow-up standard diagnostic CT in place of standard-dose CT in order to reduce the radiation dose. Springer International Publishing 2013-08-21 /pmc/articles/PMC3755805/ /pubmed/24010047 http://dx.doi.org/10.1186/2193-1801-2-393 Text en © Ono et al.; licensee Springer. 2013 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Ono, Koji
Hiraoka, Toru
Ono, Asami
Komatsu, Eiji
Shigenaga, Takehiko
Takaki, Hajime
Maeda, Toru
Ogusu, Hiroyuki
Yoshida, Shintaro
Fukushima, Kiyoyasu
Kai, Michiaki
Low-dose CT scan screening for lung cancer: comparison of images and radiation doses between low-dose CT and follow-up standard diagnostic CT
title Low-dose CT scan screening for lung cancer: comparison of images and radiation doses between low-dose CT and follow-up standard diagnostic CT
title_full Low-dose CT scan screening for lung cancer: comparison of images and radiation doses between low-dose CT and follow-up standard diagnostic CT
title_fullStr Low-dose CT scan screening for lung cancer: comparison of images and radiation doses between low-dose CT and follow-up standard diagnostic CT
title_full_unstemmed Low-dose CT scan screening for lung cancer: comparison of images and radiation doses between low-dose CT and follow-up standard diagnostic CT
title_short Low-dose CT scan screening for lung cancer: comparison of images and radiation doses between low-dose CT and follow-up standard diagnostic CT
title_sort low-dose ct scan screening for lung cancer: comparison of images and radiation doses between low-dose ct and follow-up standard diagnostic ct
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755805/
https://www.ncbi.nlm.nih.gov/pubmed/24010047
http://dx.doi.org/10.1186/2193-1801-2-393
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