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The Development of a Monoclonal Antibody Recognizing the Drosophila melanogaster Phosphorylated Histone H2A Variant (γ-H2AV)

The recognition of DNA double-strand breaks (DSBs) using a phospho-specific antibody to the histone 2A variant has become the gold standard assay for DNA damage detection. Here we report on the development of the first monoclonal antibody to the phospho-specific form of Drosophila H2AV and character...

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Detalles Bibliográficos
Autores principales: Lake, Cathleen M., Korda Holsclaw, Julie, Bellendir, Stephanie P., Sekelsky, Jeff, Hawley, R. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755914/
https://www.ncbi.nlm.nih.gov/pubmed/23833215
http://dx.doi.org/10.1534/g3.113.006833