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LRRK2 and RIPK2 Variants in the NOD 2-Mediated Signaling Pathway Are Associated with Susceptibility to Mycobacterium leprae in Indian Populations

In recent years, genome wide association studies have discovered a large number of gene loci that play a functional role in innate and adaptive immune pathways associated with leprosy susceptibility. The immunological control of intracellular bacteria M. leprae is modulated by NOD2-mediated signalin...

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Detalles Bibliográficos
Autores principales: Marcinek, Patrick, Jha, Aditya Nath, Shinde, Vidyagouri, Sundaramoorthy, Arun, Rajkumar, Raja, Suryadevara, Naveen Chandra, Neela, Sanjeev Kumar, van Tong, Hoang, Balachander, Vellingiri, Valluri, Vijaya Lakshmi, Thangaraj, Kumarasamy, Velavan, Thirumalaisamy P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756038/
https://www.ncbi.nlm.nih.gov/pubmed/24015287
http://dx.doi.org/10.1371/journal.pone.0073103